Homemade Turkey Tetrazzini
Homemade Turkey Tetrazzini is the perfect recipe for Thanksgiving leftovers with chunks of turkey, peas, mushrooms, and a rich cream sauce. So easy and delicious that my family expects it every year after the holiday!!
Years ago, I tried this Turkey Leftover Recipe on a whim and it was so well-loved by the family that it’s now a post-Thanksgiving tradition!
Why You’ll Love this Turkey Casserole
- It’s a terrific way to use up the last of the Thanksgiving turkey.
- Made with a creamy sauce, it’s delicious!
- If my picky family approves, then yours will, too.
I did not grow up eating tetrazzini, in fact, I don’t even think I knew what it was when I was leafing through my Joy of Cooking the day after Thanksgiving years ago. The recipe called for chicken (but I knew I could sub turkey), noodles, mushrooms, and cream, all of which I had on hand. I add peas for a pop of color and to incorporate a vegetable into the dish.
This homemade turkey casserole was meant to be. Making this casserole has become a once-a-year event.
The next Thanksgiving, I was asked to make this turkey leftover recipe again. Apparently, the kiddos, who were not usually fans of casserole-type dishes, approved. So our annual tradition is to eat days and days of leftover turkey, mashed potatoes, and stuffing. When there is only a bit of meat clinging to the bones, I cross my fingers and hope to pick off at least three cups from the carcass so I can whip up this tetrazzini recipe.
How to Make Turkey Tetrazzini
- Cut leftover turkey into bite-sized chunks or shred into bite-sized pieces.
- Cook pasta in salted water, drain.
- Saute mushrooms and taste for seasoning.
- Make the sauce with chicken broth.
- Add warm cream to the sauce.
- Toss the pasta, turkey, mushrooms, peas with the cream sauce.
- Pour into a casserole dish, sprinkle with Parmesan, if desired, and bake until lightly browned and heated through.
Frequently Asked Questions
What is Tetrazzini?
The original dish is a rich entree made with spaghetti, strips of chicken, and a sauce of sherry, Parmesan, and cream. It is topped with bread crumbs or Parmesan and baked until hot and bubbly.
It was said to be named after Luisa Tetrazzini, an opera singer. It is not an Italian dish, but instead American. Turkey is often substituted for chicken.
What is the Difference Between Tetrazzini and Alfredo?
Both tetrazzini and Alfredo have a sauce made with cream and Parmesan. Alfredo also has butter and is served tossed with wide, flat fettuccine pasta. Tetrazzini is traditionally made with spaghetti and is baked.
What Else Can Be Added to Tetrazzini?
Though chicken is most classic, and turkey is an obvious substitution, shrimp is also a tasty addition. Peas are not classic but a nice addition, or even the combination of frozen peas and carrots.
For an extra cheesy casserole, add some shredded mozzarella or white cheddar towards the end of the baking time.
Can You Make Tetrazzini Ahead of Time?
Yes, it can be prepped the day before and placed in a casserole dish. Cover tightly and store overnight in the refrigerator. The baking time will need to be extended when cooking a cold casserole.
How to Store Leftover Tetrazzini?
Keep it covered tightly in the refrigerator for 3-4 days. Leftovers can be frozen for up to 3 months if stored airtight. Just defrost overnight in the refrigerator before reheating.
Turkey Leftover Recipes
Today, I’m sharing one of our favorite recipes utilizing Thanksgiving leftovers, and much as I’d like to cook up something new and different, Turkey Tetrazzini is always on our menu the weekend after the holiday. And I don’t mind one bit.
There is always some cream in the refrigerator, leftover from whipping up a bowlful to dollop on our pumpkin pie. Grated Parmesan, frozen peas, chicken broth, and pasta are also staples. I just make sure to have fresh mushrooms on hand, though a jar or can of mushrooms is a wonderful pantry alternative.
Transformed from Thanksgiving leftovers, I hope you’ll give this homemade turkey tetrazzini recipe a try. Don’t forget to try it with chicken for the rest of the year!
Tip of the Day: For those gravy impaired like me, Wondra“quick mixing” flour blends easily without forming lumps. (affiliate link)
What to Serve with Tetrazzini
Tetrazzini has protein, carbs, and a smattering of vegetables, but a couple of side dishes are a nice addition to the menu. Garlic Bread is wonderful, plus a tossed green salad. Roasted vegetables like Parmesan Green Beans or Balsamic Carrots are delicious additions, too.
More Recipes Using Thanksgiving and Turkey Leftovers!
- Sweet Potato Biscuits by Home Cooking Memories
- Pumpkin Gingersnap Truffles by Chocolate Moosey
- Curried Turkey Salad
- Turkey Enchilada Casserole
- Leftover Turkey Tortilla Soup
- Turkey and Brie Grilled Cheese
- 25+ Thanksgiving Recipes
- More Holiday Recipes
This recipe was first shared in November 2012. The photos and text were updated in 2019.
- 3 cups shredded or cubed cooked turkey meat
- 1/2 pound pasta, I use orcchiette or farfalle, cooked in well-salted water and drained
- 1/2 pound (or more!) mushrooms, trimmed and cut in half or sliced
- 3 tablespoons sherry (or white wine)
- 3 tablespoons butter
- 3 tablespoons flour (Wondra preferred as it doesn't lump)
- 2 cups of chicken broth
- 1 cup heavy cream, warmed ( I gently heat in the microwave in a Pyrex measuring cup)
- 1 cup frozen peas
- Salt and pepper to taste
- Grated Parmesan cheese
- Preheat oven to 375°.
- Sauté mushrooms in butter in a large saucepan till lightly browned. Add salt and pepper to taste. Deglaze the pan by adding sherry, cooking, and stirring until most evaporates.
- Remove mushrooms and add flour to the pan. Cook for just a minute, then add the chicken broth, whisking to avoid lumps. Cook till the mixture thickens slightly.
- Add the warm cream and stir to combine.
- Remove from heat. Add the turkey, peas, and reserved mushrooms.
- Taste for seasoning, and add more salt and pepper as needed.
- Place pasta into a 9 x 13-inch baking dish (I use a smaller dish for a deeper casserole).
- Add the chicken, mushrooms, and peas, and sauce to the pasta. Mix to combine.
- Sprinkle with Parmesan. (Alternatively, toss the pasta with the sauce, chicken, mushrooms, and peas.
- Bake till lightly browned and heated through, about 15-20 minutes.
Adapted from The Joy of Cooking
Amount Per Serving: Calories: 329Total Fat: 18gSaturated Fat: 10gTrans Fat: 1gUnsaturated Fat: 6gCholesterol: 98mgSodium: 423mgCarbohydrates: 21gFiber: 2gSugar: 3gProtein: 21g